Outputs

Dissemination Material



COMBAR Publications

  • Resistance of strongylid nematodes to anthelmintic drugs and driving factors at Czech goat farms.Vadlejch J., Kyriánová I.A., Várady M., Charlier J., 2021. BMC Vet Res 17, 106.
    https://doi.org/10.1186/s12917-021-02819-8
  • Prevalence of anthelmintic resistance of gastrointestinal nematodes in Polish goat herds assessed by the larval development test.Mickiewicz M., Czopowicz M., Moroz A., Potărniche A.V., Szaluś-Jordanow O., Spinu M., Górski P., Markowska-Daniel I., Várady M., Kaba J., 2021. BMC Veterinary Research 17, 19.
    https://doi.org/10.1186/s12917-020-02721-9
  • Increasing importance of anthelmintic resistance in European livestock: creation and meta-analysis of an open database.Rose Vineer H., Morgan E.R., Hertzberg H., Bartley D.J., Bosco A., Charlier J., Chartier C., Claerebout E., de Waal T., Hendrickx G., Hinney B., Höglund J., Ježek J., Kašný M., Keane O.M., Martínez-Valladares M., Mateus T.L., McIntyre J., Mickiewicz M., Munoz A.M., Phythian C.J., Ploeger H.W., Vergles Rataj A., Skuce P.J., Simin S., Sotiraki S., Spinu M., Stuen S., Thamsborg S.M., Vadlejch J., Varady M., von Samson-Himmelstjerna G., Rinaldi L., 2020. Parasite, 27 (2020) 69
    https://doi.org/10.1051/parasite/2020062
  • A qualitative market analysis applied to Mini-FLOTAC for diagnosis of helminth infections in ruminants.Maurelli M.P., Dourado Martins O.M., Morgan E.R., Charlier J., Cringoli G., Mateus T.L., Bacescu B., Chartier C., Claerebout E., de Waal T., Helm C., Hertzberg H., Hinney B., Höglund J., Kyriánová I.A., Mickiewicz, M., Petkevičius S., Simin S., Sotiraki S., Tosheska M., Toth M., Martínez-Valladares, Varady M., Sekovska B., von Samson-Himmelstjerna G., Rinaldi L., 2020. Frontiers in Veterinary Science 7, 580649.
    https://doi.org/10.3389/fvets.2020.580649
  • The threat of reduced efficacy of anthelmintics against gastrointestinal nematodes in sheep from an area considered anthelmintic resistance-free.Bosco A., Kiessler J., Amadesi A., Varady M., Hinney B., Ianiello D., Maurelli M.P., Cringoli G., Rinaldi L., 2020. Parasites Vectors 13: 457.
    https://doi.org/10.1186/s13071-020-04329-2
  • Assessment of the F200Y mutation frequency in the β tubulin gene of Haemonchus contortus following the exposure to a discriminating concentration of thiabendazole in the egg hatch test.Baltrušis P., Komáromyová M., Várady M., von Samson-Himmelstjerna G., Höglund J., 2020. Exp Parasitol 217, 107957.
    https://www.sciencedirect.com/science/article/pii/S0014489420302411?via%3Dihub
  • Feeding of carob (Ceratonia siliqua) to sheep infected with gastrointestinal nematodes reduces faecal egg counts and worm fecundity.Saratsi K., Hoste H., Voutzourakis N., Tzanidakis N., Stefanakis A, Thamsborg S.M., Mueller-Harvey I., Hadjigeorgiou I., Sotiraki S., 2020. Vet Parasitol 284, 109200.
    https://www.sciencedirect.com/science/article/pii/S0304401720301801?dgcid=coauthor
  • The first report of multidrug resistance in gastrointestinal nematodes in goat population in Poland.Mickiewicz M., Czopowicz M., Kawecka-Grochocka E., Moroz A., Szalus-Jordanow O., Varady M., Königova A., Spinu M., Gorski P., Bagnicka E., Kaba J., 2020. BMC Vet Res 16: 270.
    https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-020-02501-5
  • Initial assessment of the economic burden of major parasitic helminth infections to the ruminant livestock industry in Europe.Charlier J., Rinaldi L., Musella V., Ploeger, H.W., Chartier, C., Rose Vineer H., Hinney B., von Samson-Himmelstjerna G., Băcescu B., Mickiewicz M., Mateus L., Martinez-Valladares M., Quealy S., Azaizeh H., Sekovska B., Akkari H., Petkevicius S., Hektoen L., Höglund J., Morgan E.R., Bartley D.J., Claerebout E., 2020. Prev Vet Med, 105103.
    https://doi.org/10.1016/j.prevetmed.2020.105103
  • Cattle gastrointestinal nematode egg‑spiked faecal samples: high recovery rates using the Mini‑FLOTAC technique. Amadesi A., Bosco A., Rinaldi L., Cringoli G., Claerebout E., Maurelli M.P., 2020. Parasites Vectors 13:230.
    https://doi.org/10.1186/s13071-020-04107-0
  • High frequency of benzimidazole resistance alleles in trichostrongyloids from Austrian sheep flocks in an alpine transhumance management system. Hinney B., Schoiswohl J., Melville L., Ameen V.J., Wille-Piazzai W., Bauer K., Joachim A., Krücken J., Skuce P.J., Krametter-Frötscher R., 2020. BMC Vet Res16:132
    https://doi.org/10.1186/s12917-020-02353-z
  • Assessment of anthelmintic efficacy against cattle gastrointestinal nematodes in western France and southern Italy. Chartier C., Ravinet N., Bosco A., Dufourd E., Gadanho M., Chauvin A., Charlier J., Maurelli M.P., Cringoli G., Rinaldi L., 2020. J Helminthol 94, e125, 1-3.
    https://doi.org/10.1017/S0022149X20000085
  • GLOWORM-PARA: a flexible framework to simulate the population dynamics of the parasitic phase of gastrointestinal nematodes infecting grazing livestock. Rose Vineer H., Verschave S.H., Claerebout E., Vercruysse J., Shaw D.J., Charlier J., Morgan E.R., 2020. Int J Parasitol, in press
    https://doi.org/10.1016/j.ijpara.2019.11.005
  • Biology and epidemiology of gastrointestinal nematodes in cattle. Charlier J., Höglund J., Morgan E.R., Geldhof P., Vercruysse J., Claerebout E., 2020. Vet Clin North Am Food Anim Pract 36, 1-15
    https://doi.org/10.1016/j.cvfa.2019.11.001
  • Hydro-Ethanolic extract of Mentha pulegium exhibit anthelmintic and antioxidant proprieties in vitro and in vivo. Sebai E., Serairi R., Saratsi K., Abidi A., Sendi N., Darghouth M.A., Wilson M.S., Sotiraki S., Akkari H., 2020. Acta Parasitologica
    https://doi.org/10.2478/s11686-020-00169-3
  • Rapid assessment of faecal egg count and faecal egg count reduction through composite sampling in cattle. Rinaldi L, Amadesi A, Dufourd E, Bosco A, Gadanho M, Lehebel A, Maurelli MP, Chauvin A, Charlier J, Cringoli G, Ravinet N, Chartier C., 2019. Parasites & Vectors 12, 353.
    https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-019-3601-x
  • Benefits of condensed tannins in forage legumes fed to ruminants: importance of structure, concentration and diet composition MUELLER-HARVEY, I.; BEE, G., DOHME-MEIER, F., HOSTE, H.,KARONEN M., KOELLIKER, R., LÜSCHER, A., NIDERKORN, V.,PELLIKAAN, W., SALMINEN, JP., SKOT, LEIF., SMITH, L., THAMSBORG, S., TOTTERDELL, P., WILKINSON, I., WILLIAMS, A., AZUHNWI , B., BAERT, N., GROSSE BRINKHAUS, A., COPANI, G., DESRUES, O., DRAKE, C., ENGSTRÖM, M., FRYGANAS, C., GIRARD, M. Crop Sciences 58, 1-25. 2019
    https://dl.sciencesocieties.org/publications/cs/abstracts/0/0/cropsci2017.06.0369
  • 100 questions in livestock helminthology research. Morgan E.R., Aziz N.A., Blanchard A., Charlier J., Charvet C., Claerebout E., Geldhof P., Greer A.W., Hertzberg H., Hodgkinson J., Höglund J., Hoste H., Kaplan R.M., Martínez-Valladares M., Mitchell S., Ploeger H.W., Rinaldi L., von Samson-Himmelstjerna G., Sotiraki S., Schnyder M., Skuce P., Bartley D., Kenyon F., Thamsborg S.M., Rose Vineer H., de Waal T., Williams A.R., van Wyk J.A., Vercruysse J., 2018. Trends Parasitol 35, 52-71. 2018
    https://www.cell.com/trends/parasitology/fulltext/S1471-4922(18)30237-X
  • Mind the gaps in research on the control of gastrointestinal nematodes of farmed ruminants and pigs. Charlier J., Thamsborg S.M., Bartley D.J., Skuce P.J., Geurden T., Hoste H., Williams A.R., Sotiraki S., Höglund J., Chartier C., Geldhof P., van Dijk J., Rinaldi L., Morgan E.R., von Samson-Himmelstjerna G., Vercruysse J., Claerebout E. Transboundary and Emerging Diseases 65(Suppl.1), 217-234. 2018
    https://onlinelibrary.wiley.com/doi/full/10.1111/tbed.12707
  • Control of helminth ruminant infections by 2030. Vercruysse J., Charlier J., Van Dijk J., Morgan E.R., Geary T., von Samson-Himmelstjerna G., Claerebout E, 2018. Parasitology, 1-10. 2018
    https://www.cambridge.org/core/journals/parasitology/article/control-of-helminth-ruminant-infections-by-2030/5E2B8A7B2CFF4E9A7AEA35E33FC7AD9A


Other relevant publications

  • Genetic variants in dyf-7 validated by droplet digital PCR are not drivers for ivermectin resistance in Haemonchus contortus. Elmahalawy S. T, Halvarsson P., Skarin M., Höglund J., 2018. International Journal for Parasitology: Drugs and Drug Resistance 8, 278-286. 2018
    https://doi.org/10.1016/j.ijpddr.2018.04.005
  • Des plantes contenant des tannins condensés : un modèle d’alicament pour gérer les vers parasites en élevages des petits ruminants. Hoste H., Torres Acosta F., Sotiraki S., Houzangbe AdoteS., Kabore A., Costa Junior L., Louvandini H., Gaudin E., Mueller Harvey I., 2018. Innovations Agronomiques 68, 19-29. 2018
    https://www6.inra.fr/ciag/content/download/6434/47664/file/Vol66-3-Hoste%20et%20al.pdf
  • Hidden in plain sight- multiple resistant species within a strongyle community. McIntyre J., Hamer K., Morrison A.A., Bartley D.J., Sargison N., Devaney E, Laing R., 2018. Veterinary Parasitology, 258, 79-87. 2018
    https://doi:10.1016/j.vetpar.2018.06.012
  • A genome resequencing-based genetic map reveals the recombination landscape of an outbred parasitic nematode in the presence of polyploidy and polyandry. Doyle S.R., Laing R., Bartley D.J., Britton C., Chaudhry U., Gilleard J.S., Holroyd N., Mable B.K., Maitland K., Morrison A.A., Tait A., Tracey A., Berriman M., Devaney E., Cotton J.A., Sargison N.D., 2018. Genome Biology and Evolution, 10(2):396-409. 2018
    https://doi:10.1093/gbe/evx269
  • Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus. Doyle S.R., Illingworth C.J.R., Laing R., Bartley D.J., Redman E, Martinelli A. Holroyd N., Morrison A.A., Rezansoff A., Tracey A., Devaney E., Berriman M., Sargison N.D., Cotton J.A., Gilleard J.S., 2019. BMC Genomics 20, 218. 2018
    https://doi:10.1186/s12864-019-5592-6



Press Releases

12/02/2018: Announcement of the network

9/10/2018: Scientists discuss research towards mitigating anthelmintic resistance in livestock

6/9/2019: Report COMBAR mid-term meeting Ghent

29/07/2020: Drug resistant parasites cost European livestock industry millions each year



Research projects

Acronym Title Duration Countries involved Funder Weblink
BUGS Building upon the Genome https://bugconsortium.wordpress.com/
ENWIR Extreme weather, nematode infection in ruminants and farmers’ responses 1/1/2019-31/12/2022 Sweden FORMAS https://www.slu.se/en/departments/biomedical-sciences-veterinary-public-health/research/parasitology/
LIFLUMILK The common liver fluke in dairy cattle – its infection dynamics and impact on the milk production 1/1/2017-31/12/2020 Sweden FORMAS https://www.slu.se/en/departments/biomedical-sciences-veterinary-public-health/research/parasitology/
MTGIN Molecular tools for detection of gastrointestinal parasites and anthelmintic resistance in sheep 1/1/2017-31/12/2020 Sweden Swedish Foundation for Agricultural Reserach (SLF) https://www.slu.se/en/departments/biomedical-sciences-veterinary-public-health/research/parasitology/
PARAGONE Vaccines for animal parasites 1/3/2015-31/3/2019 UK, Ireland, Spain, Norway, Germany, Belgium, Uruguay EU H2020 https://www.paragoneh2020.eu/
PDMAFAM Parasitic diseases and markers for the assessment of animal welfare with applications in grazing livestock 1/1/2017-31/12/2020 Sweden FORMAS https://www.slu.se/en/departments/biomedical-sciences-veterinary-public-health/research/parasitology/
PIOSF Parasite intervention in organic sheep flocks 1/1/2017-31/12/2020 Sweden SLU-Ekoforsk https://www.slu.se/en/departments/biomedical-sciences-veterinary-public-health/research/parasitology/
Proteolysis in eggs of parasitic worms (Schistosoma mansoni and Fasciola hepatica): role in pathology and its regulation 1/01/2019-31/12/2021 1 Grant Agency of Czech Republic https://sites.google.com/view/fasciola-hepatica
MERINOparasite Identification of genetic markers underlying genetic resistance to internal parasites in the Merina Branca sheep breed using the OvineHD Beadchip array 01/10/2018 – 01/10/2021 Portugal FCT https://projects.iniav.pt/merinoparasite/en/